Home > Academics > Academic Units > Faculty of Sciences (FoS) > Education > Apramita Chand
My research interests are focussed on the structure, dynamics. and hydrogen bonding properties of biomolecules in different co-solvent environments. I have worked with model peptides like FA, NMF, and NMA as well as with small peptides like cholecystokinin-8 and enkephalins to gauge the interaction patterns and conformational dynamics in aqueous cocktails of structure modifying co-solvents like DMSO, ethanol, TFE, biocompatible ionic liquids, as well as osmolytes like urea, TMAO, and taurine, in various compositions and thermodynamic conditions. My current research work is inclined towards prevention of protein misfolding through chaperone assistance, binding mechanisms, as well as co-solvents as therapeutic interventions.
I'm also deeply interested in the development of innovative pedagogical interventions in the domain of chemistry education.
The prodigious hydrogen bonds with sulfur and selenium in molecular assemblies, structural biology, and functional materials by Chand A., Sahoo D. K., Rana A. , Jena S. , Biswal H. S. Accounts of Chemical Society 53 1580-1592 (2020)
Hydrogen Bond Structure and Dynamics of cis and trans conformers of N-methylformamide in water, DMSO and water-DMSO mixtures of varying compositions by Chand A., Chettiyankandy P. , Ghosh R. , Parida C. , Chowdhuri S. Journal of Molecular Liquids 361 119610- (2022)
Effects of Urea on the Aqueous Solvation Structure and Dynamics of cis/trans-N-methylformamide: An Insight from Molecular Dynamics Simulation Study. by Parida C., Chettiyankandy P. , Chand A. , Chowdhuri S. Chermical Physics Impact 8 100448-100448 (2024)
Hydrogen-bond-driven thiouracil dissolution in aqueous ionic liquid: A combined microscopic, spectroscopic and molecular dynamics study by Sahoo D. K., Chand A. , Jena S. , Biswal H. S. Journal of Molecular Liquids 319 114275- (2020)
Computational methods for developing novel antiaging interventions by Chand A., Chettiyankandy P. , Moharana M. , Sahu S. N., Pradhan S. K., Pattanayak S. K., Mohapatra S. P., Bissoyi A. , Singh A. K. Molecular basis and emerging strategies for anti-aging interventions 175-193 (2018)
Application of Computer Simulation in Exploring Influence of Alcohol on Aqueous Milieu of a Gut- Brain Octapeptide, Cholecystokinin-8 by Chand A., Chettiyankandy P. , Chowdhuri S. Soft Computing for Problem Solving 25-40 (2019)
A comparative study of hydrogen bonding structure and dynamics in aqueous urea solution of amides with varying hydrophobicity: Effect of addition of trimethylamine N-oxide (TMAO) by Chand A., Chowdhuri S. Journal of Molecular Liquids 242 70-81 (2017)
Effects of dimethyl sulfoxide on the hydrogen bonding structure and dynamics of aqueous N-methylacetamide solution by Chand A., Chowdhuri S. Journal of Chemical Sciences 128 991-1001 (2016)
A Molecular Dynamics Simulation Study of Osmolyte Effects on Solution Conformations of [Met]- Enkephalin by Chand A., Rao K. S., Chowdhuri S. National Conference on Physics and Chemistry of Materials - (2021)